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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
13.64
Human Site:
S244
Identified Species:
23.08
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
S244
P
G
N
G
T
P
C
S
Q
D
T
S
F
S
S
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
S244
P
G
N
G
T
P
C
S
Q
D
T
S
F
S
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
S252
N
S
G
G
T
P
F
S
Q
D
T
A
Y
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
Chicken
Gallus gallus
Q5F3P8
2008
223067
S303
P
R
L
G
T
P
F
S
Q
D
S
T
Y
S
S
Frog
Xenopus laevis
Q66J90
1938
216239
S270
S
H
D
T
A
Y
S
S
S
R
Q
G
T
P
N
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
T289
N
T
P
M
S
L
D
T
A
Y
S
S
L
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
N246
Q
T
N
H
E
I
P
N
R
S
R
D
R
N
W
Honey Bee
Apis mellifera
XP_395451
1406
159180
N64
Q
T
P
Q
K
P
R
N
Y
K
L
L
V
D
P
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
R165
C
I
H
P
E
T
K
R
H
M
K
M
A
Y
V
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
Q310
Y
A
Q
Q
T
P
V
Q
Q
V
Q
E
G
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
0
N.A.
60
N.A.
N.A.
0
60
6.6
6.6
N.A.
6.6
6.6
0
20
P-Site Similarity:
100
100
N.A.
0
N.A.
73.3
N.A.
N.A.
0
80
20
26.6
N.A.
26.6
13.3
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
0
8
0
0
8
8
0
0
% A
% Cys:
8
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
8
0
0
29
0
8
0
8
0
% D
% Glu:
0
0
0
0
15
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
15
0
0
0
0
0
15
8
0
% F
% Gly:
0
15
8
29
0
0
0
0
0
0
0
8
8
0
0
% G
% His:
0
8
8
8
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
8
0
0
8
8
0
0
0
0
% K
% Leu:
0
0
8
0
0
8
0
0
0
0
8
8
8
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
8
0
8
0
0
0
% M
% Asn:
15
0
22
0
0
0
0
15
0
0
0
0
0
8
8
% N
% Pro:
22
0
15
8
0
43
8
0
0
0
0
0
0
8
8
% P
% Gln:
15
0
8
15
0
0
0
8
36
0
15
0
0
0
8
% Q
% Arg:
0
8
0
0
0
0
8
8
8
8
8
0
8
8
0
% R
% Ser:
8
8
0
0
8
0
8
36
8
8
15
22
0
29
29
% S
% Thr:
0
22
0
8
36
8
0
8
0
0
22
8
8
0
8
% T
% Val:
0
0
0
0
0
0
8
0
0
8
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
8
0
0
0
0
8
0
0
8
8
0
0
15
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _